Chemotherapy toxicity

Chemotherapy toxicity - #37

Take Quiz

Review toxic affects of chemo therapy on geriatric patients.

A geriatric patient with cancer, in the outpatient or inpatient clinical setting.

Determine potential chemotherapy toxicities to elderly patients undergoing treatment for cancer.

• List 3 crucial questions to ask when assessing an elderly patients appropriateness for chemotherapy treatment.
• Identify potential toxicities associated with common chemotherapy agents.

 

  1. SEER cancer statistics review 1975-2010. National Cancer Institute, http://seer.cancer.gov/csr/1975_2010/.
  2. Cancer facts and figures 2013. American Cancer Society, http://www.cancer.org/research/cancerfactsstatistics/cancerfactsfigures2...
  3. Hurria A, Browner IS, Cohen HJ, Denlinger CS. NCCN Guidelines: Senior Adult Oncology. J Natl Compr Canc Netw, 2012; 10:162-209.
  4. Repetto L. Greater risks of chemotherapy toxicity in elderly patients with cancer. J Support Oncol 2003; 1(suppl 2): 18-24.
  5. ECOG Common Toxicity Criteria. Eastern Cooperative Oncology Group. Rober Comis MD, Group Chair. http://ecog.dfci.harvard.edu/general/ctc.pdf
  6. Hurria A, Togawa K, Mohile SG, et al. Predicting chemotherapy toxicity in older adults with cancer: a prospective multicenter study. J Clin Oncol 2011; 29: 3457-3465.
  7. Sawhney R, Sehl M, Naeim A. Physiologic aspects of aging: impact on cancer management and decision making, part I. Cancer J 2005; 11: 449-460.
  8. Sehl M, Sawhney R, Naeim A. Physiologic aspects of aging: impact on cancer management and decision making, part II. Cancer J 2005; 11:461-473.
  9. Lichtman SM, Wildiers H, Chatelut E, et al. International society of geriatric oncology chemotherapy taskforce: evaluation of chemotherapy in older patients-an analysis of the medical literature. J Clin Oncol 2007; 25: 1832-1843.
  10. Gonsalves W, Ganti AP. Targeted anti-cancer therapy in the elderly. Crit Rev Oncol Hematol 2011; 78: 227-242.
You voted '2'.
This GFF ___ my competence in geriatrics.

Thomas Giever DO, Kathryn Denson MD, Nicholas Dreger, Patrick Foy MD, Gabriel Manzi MD

Medical College of Wisconsin