Antiplatelet Therapy in Coronary Disease - #23
Take QuizReview antiplatelet therapy in coronary artery disease.
Discontinuation of antiplatelet therapy:
- Discontinue dual antiplateleting
- Continue aspirin for one year
NOTE: See graphs depicting intervention/prevention. Tap on graph for clear image
Fig 1: Choices for Antiplatelet Therapy and Mechanism of Action
Fig 2 : Recommendations for Primary Prevention
Fig 3: Recommendations for Secondary Intervention
Geriatric patient with coronary artery disease (CAD).
Provide antiplatelet therapy recommendations in CAD patients with/without coronary stents.
Age is an important determinant of outcome in patients with coronary artery disease. Antiplatelet therapy has been shown to improve outcomes, however, antiplatelet agents are prescribed less in the advanced age group due to limited trial data guiding care and uncertainty about benefit/risk, complex health status, and medication interactions.
Science Principles
In patients with coronary artery disease:
- List the choices for antiplatelet therapy and their mechanism of action.
- List current recommendations regarding type and duration of antiplatelet therapy in patients with/without coronary stents.
Review of Systems (ROS)
Geriatric Topics
ACGME Compentencies
Science Principles
- Braunwald E, Antman EM, Beasley JW, Califf RM, Cheitlin MD, Hochman JS, Jones RH, Kereiakes D, et al. ACC/AHA 2002 guideline update for the management of patients with unstable angina and non-ST-segment elevation myocardial infarction: summary article: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on the Management of Patients With Unstable Angina), J Am Coll Cardiol 2002. 40(7) 1366-1374. http://www.ncbi.nlm.nih.gov/pubmed/12383588
- Vandvik PO, Lincoff AM, Gore JM, Gutterman DD, Sonnenberg FA, Alonso-Coello P, MD, Akl EA, Lansberg MG, Guyatt GH, Spencer FA, American College of Chest Physicians. Primary and Secondary Prevention of Cardiovascular Disease Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest 2012. 141(2 suppl):e637s-68s. http://www.ncbi.nlm.nih.gov/pubmed/22315274
Users are free to download and distribute Geriatric Fast Facts for informational, educational, and research purposes only. Citation: Guru Krishnan, Kathryn Denson MD, Gabriel Manzi MD, Diane Brown, Fast Fact #23: Antiplatelet Therapy in Coronary Disease, February, 2013.
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